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Kota J, Handy CR, Haidet AM, Montgomery CL, Eagle A, Rodino-Klapac LR, et al

Control of mitochondrial protein glutathionylation (Prot-S-SG, Prot -SH) by glutaredoxin (GRX2) and thioredoxin 2 (TRX2)

It plays a vital role in wound healing, angiogenesis, and cellular remodeling, and is studied extensively for its influence on collagen synthesis, anti-inflammatory signaling, and gene expression associated with skin and organ repair

JO: Data curation, Writing original draft

Clinical trials of tirzepatide, a dual GLP-1 and glucose-dependent insulinotropic peptide (GIP) receptor agonist, reported constipation in approximately 2527% of participants at therapeutic doses