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Injectable vials are the format used in every published animal study, but those used intraperitoneal injection in mice not subcutaneous injection in humans

Subsequent human studies including the 2016 Lee et al

The mechanism researchers find most interesting is angiogenesis, the growth of new blood vessels

Overall, flavonoids act on multiple pathogenic targetsoxidative stress, inflammation, mitochondrial dysfunction, and protein aggregationto confer neuroprotection, supporting epidemiological observations that flavonoid-rich diets may help prevent or slow the progression of PD

While effective for immediate symptom resolution, this approach shuts down endogenous production by triggering a negative feedback loop