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doi: 10.3389/fmed.2026.1730795 Received 23 October 2025 Revised 06 March 2026 Accepted 23 March 2026 Published 02 April 2026 Corrected 05 June 2026 Volume 13 - 2026 Edited by Andrea Tinelli, Veris Delli Ponti Hospital, Italy Reviewed by Feng Zhang, Nanjing University of Chinese Medicine, China Minghong Sun, Southwest University, China Updates Copyright 2026 Lv, Li, Ding and Kuang

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(2020) 8:e14373

However, the use of oxygen within the body increases the energy available for use by its cells 20-fold, and aerobic metabolism allowed an explosion of development within the animal kingdom leading the great diversity of organisms that we see today