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doi: 10.3109/07357900902849640

One detail that shapes the clinical narrative is that plasma DSIP levels show a diurnal pattern , reported as lower in the morning and higher in the evening

As laboratory projects become more multi-layered and time-resolved, documentation quality becomes a larger determinant of whether results remain comparable across timepoints, operators, and study phases

Definition of diabetic peripheral neuropathy The clinical diagnosis of diabetic peripheral neuropathy (DPN) was determined using a questionnaire (Neuropathy Symptom Score) and physical examination (Neuropathy Deficit Score), which were performed by an experienced neurologist on all patients, as described previously [30]

NMDA receptor modulation is consistent with DSIPs observed effects on cortical EEG activity, delta-wave induction, and neuroprotective properties in stroke and hypoxia models