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Recent studies have found that circulating TMAO can promote vascular calcification in rats with CKD and activates the NLRP3 inflammasome and NF-B signaling pathways (Zhang et al., 2020)

The retrieved data included study characteristics, characteristics of patients, interventions, and outcome measures, that included the hazard ratios (HR) and confidence intervals (CI) for cardiorenal outcomes

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K.ManivasagamT.et al (2013)