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Yet too often, ads minimized risks or promoted unrealistic outcomes

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Several trials, such as the United Kingdom Prospective Diabetes Study (UKPDS) and Action in Diabetes and Vascular Disease: Preterax and Diamicron MR Controlled Evaluation (ADVANCE), have demonstrated that appropriate control of blood glucose is beneficial for the reduction of long-term cardiovascular complications [4, 5]

Over the same period, public interest in these drugs exploded as well, with Google searches for "GLP-1" increasing twentyfold

Two rules hold across all three rows