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The NLRP3 inflammasome is a complex consists of a sensor (NLRP3 protein), an adaptor (apoptosis-associated speck-like protein, ASC), and an effector (caspase-1)

Brighten: I wanna ask about modifiable risk factors, but in terms of early screening, do you think we should be advocating for imaging for doing more testing to screen [00:07:00] people for neurodegenerative disease rather than waiting until there's those first symptoms