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The cysteine desulfhydrase (CD) catalyzes the degradation of l-cysteine, and two cysteine desulfhydrases, tryptophanase encoded by tnaA and cystathionine -lyase encoded by metC ), are mainly responsible for the l-cysteine degradation in E

Gastrointestinal AE with cagrisema were more than with semagutide or cagrilintide monotherapy, however the SAE and AE leading to medication discontinuation were minimal and similar between the groups [87, 90] A programme of phase 3 clinical trials (REDEFINE) assessing the safety and efficacy of cagrisema in people with obesity (NCT05567796, NCT05394519, NCT05813925) is currently ongoing

doi: 10.1038/s41564-020-0756-3 53 HollaS.Kurowska-StolarskaM.BayryJ.BalajiK

A more severe clinical condition (such as with advanced fibrosis) is correlated with higher abundance of C

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