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Ive observed that there are 5 obstacles patients experience with these medications as treatments for obesity and diabetes: Cost of the meds Side effects and tolerability Fear of needles Concerns about safety The moral failing of needing a medication Oral GLP1 drugs like orforglipron (Foundayo) and Wegovy work almost as well as the injectable version of these drugs The FDA just approved oral Foundayo for the treatment of obesity based on the results of the ATTAIN-1 trial, recently published in NEJM

Financial accessibility makes probiotic GLP-1 support potentially relevant for several consumer segments: individuals without insurance coverage for weight management medications, for whom pharmaceutical options are financially inaccessible regardless of efficacy

Physicians can respond quickly to side effects, adjust protocols, and modify treatment plans without insurance company interference

When used alongside other glucose-lowering agents, semaglutide may increase the risk of hypoglycemia, necessitating dose adjustments of concomitant medications

Evaluation of oral and topical bovine colostrum compared to mesalamine in the treatment of animal model of acetic acid-induced ulcerative colitis