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The GIP component enhances insulin sensitivity in fat tissue and may promote beneficial fat metabolism, building on the same principle that makes tirzepatide dosing effective

Most GLP-1 medications use modified peptides that resist breakdown in the body, allowing them to stay active longer and require only once-daily or once-weekly dosing

For eliminating the potential baseline effect of different studies, the rates of body weight change from the initial values were selected as the therapeutic index

NP4 reached a maximal oxygen storage of 53 mg/L, which was approximately 2.5 more than for NP2 (Supplementary Fig

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