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Benefits of L-Carnitine Supplements There are numerous benefits of l carnitine supplements, including their roles in fat metabolism, exercise performance, and recovery

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They are used as an adjunct within supervised medical weight-loss programmes, not as a standalone treatment

Notably, the IL-6/JAK2/STAT3 pathway exhibits bidirectional regulation: it promotes the accumulation of PUFAs by activating fatty acid synthase (FASN), thereby increasing the risk of ferroptosis, while simultaneously inhibiting CRT exposure to weaken the immunogenicity of ICD (Johnson et al., 2020) (201)