Adequate Vitamin B12 status helps support a healthy mood, and B12 supplementation can help reduce fatigue for those low in Vitamin B12
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Multiple human studies have confirmed zero impact on fasting glucose, insulin, HbA1c, or IGF-1 levels (Thompson et al., 2004)
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However, it can also be the result of low B6, low folate, renal failure, or hypothyroidism