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discovered that iron supplementation could alter gut microbial homeostasis and exacerbate intestinal inflammation in a murine model of CD (138)

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At the end of 16 weeks, the animals were fasted overnight and then euthanized by exposure to isoflurane (Webster Veterinary Supply Inc., Devens, MA)

With the sustained development of disease-modifying antirheumatic drugs (DMARDs), significant success has been achieved for preventing and relieving disease activity in RA patients

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