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Szab D, Tod P, Glncsr F et al (2022) Maternal P2X7 receptor inhibition prevents autism-like phenotype in male mouse offspring through the NLRP3-IL-1 pathway

Even though it is coconut derived, the problematic lauric acid is stripped out

The threshold of 90 ml/min/1.73 m 2 has been chosen in accordance with KDIGO guidelines

Downstream Signaling Pathways Following target engagement, several downstream signaling cascades have been reported in experimental models

Methods Samples In this study, 3D InSight TM Human Cardiac Microtissues (InSphero, for beta-testers) were used, containing a co-culture of approximately 4000 iPSC-derived human cardiomyocytes from a female Caucasian donor with no known disease phenotype and 1000 cardiac fibroblasts from an 18 year old Caucasian male