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Clinical evidence supporting pharmacologic treatment of obesity.

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In the hippocampus, for example, estrogen binding to ER and ER has been shown to promote the expression of genes involved in synaptic plasticity, neurogenesis, and neuronal survival [67]

In a 2-year global study (involving 304 people), adults taking Wegovy , in addition to a reduced-energy diet and increased physical activity, lost an average of 15.2% of their body weight compared to 2.6% in those taking placebo

More than a third had less scarring (fibrosis) of their liver