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Methods 12 , 11431149 (2015)

High acidic conditions accelerate the release of iron ions with enhanced Fenton reaction efficiency

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The clinical implication of our findings is to use TdGSH to prevent progressive loss of -cell mass in diabetic patients, who have more glycaemic variabilities because of the vicious metabolic memory obtained from the disease, and to block the development of diabetic complications

This model expresses Cre recombinase under the control of the neuron-specific Map2 promoter, allowing for targeted deletion of Slc25a39 upon tamoxifen induction (Fig