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The changes at the genus level also exhibited significant differences ( Pseudomonas aeruginosa infection can elicit a robust inflammatory response, thereby altering the diversity and composition of the gut microbiota

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The pharmacodynamics of ALT-801, a GLP-1/glucagon receptor dual agonist optimized for NASH and weight loss, were compared to semaglutide (GLP-1 receptor agonist) and elafibranor (peroxisome proliferator-activated receptor, PPAR-/, agonist) in a biopsy-confirmed, diet-induced obese (DIO) mouse model of NASH (DIO-NASH)