ozempic semaglutide or tirzepatide In adults with obesity but not diabetes, leads to significantly greater weight loss than over 72 weeks, and nearly double the patients on tirzepatide meet the 25% weight-loss target. http://ms.spr.ly/6183SkuIL What's The Difference between Semaglutide

[1] [6] Beyond its glucose-lowering effects, semaglutide has been associated with modest improvements in several cardiovascular risk factors, including modest blood pressure reduction and weight loss

Despite the glucagon receptor agonism which might theoretically raise blood glucose net glycaemic effects in the Phase 2 obesity trial (conducted in adults without diabetes) were favourable, likely because the GLP-1 and GIP components counterbalance glucagon's glucose-raising effects

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If larger-scale prospective trials confirm the findings, GLP-1 agonists could potentially be explored as adjuncts to existing breast cancer prevention strategies

The Bottom Line GLP-1 therapy is a breakthrough, but it isnt a silver bullet