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Swelling: The skin may become puffy or swollen, particularly around the eyes or lips

Clinical trial data and post-marketing surveillance have documented gastrointestinal complaints in a substantial proportion of patients, with nausea being the most frequent (reported in 1540% of patients depending on the specific agent and dose), followed by vomiting, diarrhoea, constipation, and dyspepsia

However, there are situations where the needs increase or the intake decreases : intense exercise, aging or diets with little animal protein (like vegetarian or vegan) are the most common

Noce A, Ferrannini M, Fabrini R, Bocedi A, Dess M, Galli F et al

However, prescribing providers will not be required to document that patients are actively participating in these lifestyle support programs as part of attesting to their eligibility for the model based on other clinical criteria