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An untrained injector can provoke mild or moderate to severe side effects with incorrect administration

TFCC tears cause pain on the outer wrist edge, especially during twisting motions

Lazic R., Gabric N., Dekaris I., Bosnar D., Boban-Blagaic A., Sikiric P

Pregnant or breastfeeding patients should discuss with their obstetric provider before starting this injection, and ensure all healthcare team members are aware, so that vitamin levels and any pregnancy-related effects can be monitored appropriately

One small pilot study in 2025 primarily reported short-term tolerability, which falls far short of proving effectiveness