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One of the sequelae is myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), which is often difficult to diagnose, having no established tests

In recent years, GLP-1 receptor agonists like Ozempic, Semaglutide and Mounjaro have made headlines as game-changers in the world of weight loss and type 2 diabetes management

Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease

Clinical management typically adopts a multidisciplinary approach that incorporates cognitive rehabilitation, management of comorbidities, and anti-inflammatory interventions to address the underlying pathophysiology [8]

Al-Aly has described this as moving from food noise to drug noise, suggesting the same biological pathway that helps patients lose interest in overeating may also quiet the pull of alcohol, nicotine, opioids and other substances