semaglutide pioneer Efficacy and safety of oral vs sitagliptin in a predominantly Chinese population with type 2 diabetes uncontrolled with metformin: 12, a double-blind, Phase IIIa, randomised trial | Diabetologia Oral Semaglutide and Cardiovascular Outcomes

Butler: Marked Expansion of Exocrine and Endocrine Pancreas with Incretin Therapy in Humans with increased Exocrine Pancreas Dysplasia and the potential for Glucagon-producing Neuroendocrine Tumors

This approach allows the gastrointestinal system to adapt to GLP-1 receptor activation, reducing the incidence and severity of nausea, vomiting, and diarrhea that often accompany rapid dose escalation

Divakar K, Pawar AT, Chandrasekhar SB, Dighe SB, Divakar G

While the plateau is common, there are some nuances to it

Similarly, a study using diffusion tensor imaging to assess white matter microstructure in pediatric concussion also failed to find differences in white matter microstructure at 11 days following injury 12 , although another study found higher mean diffusivity in the thalamic radiation 3 months post-injury and reductions in mean diffusivity of the arcuate fasciculus at 6 months post-injury 13