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Some experience mild digestive adjustments like bloating, gas, or changes in bowel habits during the first week

In the SURMOUT-1 trial 2,539 patients underwent randomization to tirzepatide or placebo and were followed for 72 weeks demonstrating up to 20.9% weight reduction with maintenance dosing versus 3.1% in the placebo group for a net 17.8% weight reduction [35]

10.2165/11534750-000000000-00000 Pubmed Abstract CrossRef Google Scholar View reference in article 5

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