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[3] [4] The cardiovascular safety profile of semaglutide has been extensively studied, with the SELECT trial (semaglutide 2.4mg in obesity with established cardiovascular disease) and SUSTAIN-6 trial (semaglutide 1.0mg in type 2 diabetes) demonstrating cardiovascular safety

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Structured weight-management programmes UK programmes such as NHS Weight Management Services or private clinics provide guidance that can complement or sometimes replace medication