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Abstract Progesterone-receptor membrane component 1 (PGRMC1/Sigma-2 receptor) is a haem-containing protein that interacts with epidermal growth factor receptor (EGFR) and cytochromes P450 to regulate cancer proliferation and chemoresistance

210 Additionally, epigenetics is associated with cardiovascular diseases, 211 metabolic diseases, 212 autoimmune disorders, 213 endocrine disruptions, 214 and aging

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