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4.2 Respiratory system inflammatory diseases Upper respiratory tract inflammation, exemplified by eosinophil-dominated chronic sinusitis, is characterized by as type 2 inflammation with an increase in eosinophils, as well as elevated production of type 2 cytokines such as IL-5 and IL-13

Secretion of S1P from pericytes and astrocytes to retinal microvasculature ECs will promote barrier stability through upregulation of various junctional proteins, as well as the expression of N-cadherin which promotes cell-to-cell interaction (Paik et al., 2004

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