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most common AEs include nausea, vomiting, and diarrhea), room for improvement exists in improving GI tolerability and patient discontinuation due to AEs

Non-surgical periodontal therapy (NSPT) reduces periodontal pathogen load by removing supra- and subgingival biofilms, leading to beneficial remodeling of the gut microbiotaoral-derived opportunistic pathogens decrease in the gut, and microbial communities in both niches shift toward a healthier profile (Baima et al., 2024)

Key Takeaway: Computing your dosage is a dynamic process

Signs of degradation: cloudiness, yellowing, visible particles, flakes, or persistent foam

Romazicon (flumazenil) package insert