In pre-marketing clinical studies of brand-name Wellbutrin SR (sustained-release bupropion) in the treatment of major depressive disorder, mild weight loss of greater than five pounds occurred in 28% of all patients receiving the medication at either a dose of 300 mg per day or 400 mg per day
Current data suggest that the oral formulation leads to clinically meaningful weight loss, but on average, it appears less effective than higher doses of high-efficacy injectable GLP-1 therapies, says Jaime Almandoz, MD, medical director of UT Southwestern Medical Centers weight wellness program
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According to the guideline, metformin remains the preferred initial pharmacologic agent for treating type 2 diabetes
Zeng C, Qiu Y, Li S, Teng Z, Xiang H, Chen J, et al
