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The safety profile of AOD-9604 is favorable compared to many metabolic interventions, with clinical trials involving approximately 900 participants demonstrating good tolerability and minimal side effects

Operating on a patient with an uncorrected B12 deficiency increases the risk of: Impaired wound healing and a higher chance of wound breakdown Post-operative fatigue and slower recovery, particularly if anaemia is also present Elevated homocysteine, which feeds into an already elevated DVT risk profile A sub-optimal immune response during the early wound healing phase None of these is certain to happen

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The association between high plasma B12 and cancer, or cancer mortality, was present in a series of cohort studies based on Danish health register data [11], whereas results of case-control studies were inconclusive

Are high doses of vitamin B12 harmful