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195 SLC39A14 (also known as Zrt- and Irt-like protein 14, or ZIP14) is a zinc transporter protein highly expressed in both the intestine and liver

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Multiple studies have reported abnormalities in mitochondrial number, density, and function in skeletal muscle using techniques such as transmission electron microscopy, OXPHOS enzymatic activity analysis, and mitochondrial substrate oxidation measurements [176,177,178]

Further study of this model and this subgroup of ASD patients should improve our understanding of the pathophysiology and potential risk factors that lead to the metabolic, brain and behavior abnormalities associated with ASD