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However, proline content declined by 10.52% with supplementation of JA over the entire investigational period in non-stressed (10 M JA + 0 mM Na 2 CO 3 ) seedlings

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To further elucidate the therapeutic mechanisms underlying D-CuPs multivalent interactions, comprehensive proteomic analysis revealed two pivotal transcriptional regulators, the tumor suppressor protein p53 and histone deacetylase 7 (HDAC7) to be potential mechanistic targets