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Acetaminophen-NAPQI Hepatotoxicity: A Cell Line Model System Genome-Wide Association Study

Instead of being broken down and causing gut irritation, the liposome travels through the digestive tract and merges directly with the cells in the small intestine

Destabilizing mutations facilitate this initial transition, and the increased rate of conversion to a pathological state likely contributes to the earlier age of onset compared with wild-type TTR amyloidosis

Importantly, after three-month treatments of animals, the nanocarriers caused significantly lower gastric damage score than the free drug