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Monitoring for Complications While taking empagliflozin, it is vital to be vigilant for signs of more severe complications, including: Diabetic Ketoacidosis (DKA): A rare but serious condition that can occur even if blood sugar levels are not very high

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Amelanotic forms may require use of immunohistochemical identification: S-100 protein, HMB-45, Melan-A expression Diagnosis Biopsy High index of suspicion Differential Diagnosis Mucosal nevus Extrinsic pigmentation Melanoacanthoma Kaposis sarcoma Vascular malformation Amalgam tattoo Mucosal melanotic macule Treatment Surgical excision Marginal parameters related to depth of invasion and presence of lateral growth Wide surgical margins