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It belongs to a class of medications called GLP-1 receptor agonists, which work by stimulating the release of insulin in response to high blood sugar levels, and by reducing the production of glucose by the liver

The ASCO GI 2026 data suggest that GLP-1 therapy may be particularly relevant for metabolically high-risk populations, including individuals with obesity, insulin resistance, or type 2 diabetesgroups that now account for a substantial proportion of colorectal cancer burden

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These effects usually are reversible after discontinuance of therapy