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Cohort entry was defined as the date of the first-ever prescription for one of the drugs of interest (GLP-1RAs, SGLT2 inhibitors, metformin or other second- or third-line glucose-lowering drugs) during the study period, and their respective first exposure was defined as the index event

Its main use is for achieving skin pigmentation

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Standard daily dose: 2 mg (2000 mcg) once daily subcutaneously (FDA-approved protocol)

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