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[459] Therefore, we believe much of the remittance data hospitals will use to encode the allowed amounts will be finalized within 13 months, and that our finalized lookback period (discussed in a later section) that includes no less than 12 months and no longer than 15 months of data prior to posting the MRF should provide sufficient time for hospitals to receive corrected remittance data for most of the data that is used

The SmPC specifically advises that the dose of insulin or sulphonylureas may need to be reduced when initiating semaglutide treatment

Are long-term effects being considered

47 The 2026 China Patent Cliff: A Global Inflection Point China, the second-largest pharmaceutical market in the world, is facing an imminent patent cliff for semaglutide

No claims are made regarding biological activity, safety, efficacy, or medical benefit