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Upon returning to Singapore, he was the sub-speciality lead for adrenal, pituitary, and bone services at Khoo Teck Puat Hospital and established The Metabolic Bone Clinic

Some participants in trials also reported fatigue, though this was not uniformly documented across all study arms

These hormonal shifts cause the prostate gland to gradually enlarge, which can press against the urethra and lead to common urinary symptoms such as difficulty starting to urinate or needing to go more frequently.h BPH itself typically does not affect a mans life expectancy, as its a noncancerous enlargement of the prostate that mainly causes urinary symptoms

At standard doses of 1 to 2 mg per day for a 70 kg person, the copper load is approximately 300-fold below the toxic threshold (Pickart & Margolina, 2018)