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Consistent with the renal benefits identified in our meta-analysis, SGLT2Is slowed eGFR decline versus placebo across both HF phenotypes in HFrEF (0.55 versus 2.28 ml/min/1.73 m per /year) and in HFpEF (1.25 versus 2.62 ml/min/1.73 m per year)

The really exciting shift is that these tools now extend beyond drug discovery

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