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Glucagon receptor activation increases hepatic glucose production (relevant for energy balance), boosts basal metabolic rate (thermogenesis), and promotes lipolysis (fat breakdown)

By mimicking the effects of the naturally occurring GLP-1 hormone, these injections help the body recognize when it is full, reducing the desire to eat more food

The resulting trimmed and de-duplicated reads were then aligned to the Rattus norvegicus Rnor6.0 reference genome, available on ENSEMBL, using STAR aligner v.2.5.2b4 25 , producing BAM files

15 nM), pemetrexed (Merck, PHR1596, lot LRAC1932