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Product analysis establishes the incorporation of one oxygen atom from water into the thiosulfate product To validate the proposed reaction in Eq 1, which ultimately leads to the formation of TS (Fig

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It is distinct from traditional forms of programmed cell death, such as apoptosis and pyroptosis, in both biochemical and cellular morphological aspects ( This review seeks to clarify the molecular mechanisms underlying ferroptosis, its significance within the bone microenvironment, and the modes of action and potential therapeutic targets associated with ferroptosis in conditions such as OP, OA, OS, and LDH