Patients experiencing significant side effects may benefit from a slower titration schedule or temporary dose reduction, and dose escalation should be deferred while significant gastrointestinal symptoms persist
DOI: Published online: February 13, 2023 1 Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea 2 Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea 3 Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea 4 Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea Corresponding author: Young Min Cho
Ethics declarations Ethics approval and consent to participate As this study is a systematic review and meta-analysis of previously published data, ethical approval was not required by the authors institutional review board
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