(2004, Annals of the New York Academy of Sciences) showed that T4 and its derived fragments greatly upregulate VEGF (vascular endothelial growth factor) expression in endothelial cells, promote endothelial tube formation in Matrigel assays, and reduce ischemic tissue loss in cardiac injury models
(PubMed) Nazeri P, Mirmiran P, Shiva N, Mehrabi Y, Mojarrad M, Azizi F
As with obesity, reduced muscle strength in sarcopenia is associated with disability and poor QoL [25], as well as risk of adverse events and subsequent hospital care, increasing the financial burden to the health service [41]
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