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Administration : Given intramuscularly (into the muscle) Types : Usually hydroxocobalamin or cyanocobalamin

The best way to do this is to bring the water to a rolling boil for 1 minute, or 3 minutes at elevations above 5,000 ft (1,000 m)

Scale back if pain increases beyond baseline, swelling returns, symptoms persist beyond 24 hours, or multiple consecutive sessions trigger increased symptoms

[1] Other rare side effects noted (mostly in older literature or high-dose use) include: polycythemia vera and peripheral vascular thrombosis in patients receiving repeated injections (though these associations are not well understood, they were listed in prior product literature as possible adverse events)

Human Evidence and Safety Human Studies: Only two very small pilot studies in humans exist (one for bladder pain, one for knee pain, each with fewer than 20 participants)7