CircRNA expression profiles of vitiligo patients before and after systemic glucocorticoids treatment were significantly different, and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways revealed that the down-regulated differential circRNAs were predominantly enriched in ferroptosis regulatory pathways
These findings from diverse PRS studies illustrate both the potential and the inherent challenges in using genetic scores to elucidate the link between MDD and T2DM
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The proposed mechanism involves PCs activating peroxisome proliferator-activated receptor (PPAR) in macrophages, upregulating PPAR target genes (CD36 and ABCG1) and driving the transition from M1 to M2 phenotypes