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It is involved in the synthesis of thymidine from deoxyuridine, promotion of deposited folate utilisation and metabolism of nucleic acid

High blood pressure High blood pressure is thought to increase the thickness and stiffness of the left ventricular walls over time, which changes the way in which electrical impulses travel through the heart (MayoClinic 2011a)

The AGEs modify soluble neurofilament proteins into insoluble aggregates, a process which occurs when RAGE binds to A peptides, thereby inducing the release of ROS and, as a consequence, favoring the oligomerization of these peptides

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[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Espins C., Galindo M.I., Garca-Gimeno M.A., Ibez-Cabellos J.S., Martnez-Rubio D., Milln J.M., Rodrigo R., Sanz P., Seco-Cervera M., Sevilla T., et al