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The Wake Forest University School of Medicine Alzheimers Disease Research Center is coordinating the study, which is sponsored by the Alzheimers Drug Discovery Foundation (ADDF)

Conventional meds, such as metformin, lower insulin levels, have a modest weight effect, and possess a long safety record

One possible explanation may be a drop in the self-administered dose occurring toward the end of the study

PloS one 2012;7, e45069, doi:10.1371/journal.pone.0045069

iGluRs are classified into three types: N-methyl-D-aspartate (NMDA) receptors, kainate receptors (KARs), and -amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors