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If you choose nasal spray despite these limitations, use approximately 1.0-1.5 mg per application (equivalent to 0.5 mg injected)

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Most experts will say that weight loss less than 20 percent after bariatric surgery defines a non-responder, or insufficient weight loss from the procedure. Amgen phase 2 study results also resulted in up to about 17 percent average weight loss and a reduction in HbA1c (average glucose over three months) up to 2.2 points among trial participants living with both obesity and type 2 diabetes

JAMA, 2020

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