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Moreover, preclinical and early phase clinical trials have confirmed the therapeutic potential of entero-pancreatic hormone combinations in obesity and/or metabolic complications such as T2D [33]

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11 Its also important to note that taking B12 in combination with vitamin B6 and folate (rather than alone) is shown to be most effective for regulating homocysteine levels for some patients and preventing the combined risk of stroke, myocardial infarction (heart attack), and damage to heart cells

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