Fatty acid induction of GLP-1 secretion has been demonstrated in vitro using murine enteroendocrine STC-1 cells [251] and human intestinal NCI-H716 cells [251,253] and in vivo by direct administration of lipids into the duodenum [288,289] or ileum [210]
These hybrids exhibited superior neuroprotective effects and lower cytotoxicity compared with curcumin alone, activated ARE, chelated ferrous ions and scavenged ROS, thereby protecting cells from oxidative stress and ferroptosis, ultimately promoting neuronal survival (104,127,128)
Food & Drug Administrations expanded approval or simply a coincidence
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