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In addition, you must meet one of the three clinical criteria set by CMS, measured at the time you start GLP-1 therapy: BMI of 35 or higher (and age 18 or older), or BMI of 30 or higher (and age 18 or older), plus one of the following: heart failure with preserved ejection fraction, uncontrolled high blood pressure (systolic above 140 or diastolic above 90 despite treatment with two blood pressure medications), or chronic kidney disease stage 3a or above, or BMI of 27 or higher (and age 18 or older), plus one of the following: prediabetes, a previous heart attack, a previous stroke, or symptomatic peripheral artery disease If you take a GLP-1 for another condition, the Bridge is not for you
Kidney Health Since the kidneys produce L-carnitine, individuals with kidney disease or those on dialysis may benefit from supplementation
In summary both MK 677 and Ipamorelin are growth hormone secretagogues with significant benefits for body composition, bone health and muscle growth
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In addition, LDL-cholesterol levels were lower and HDL-cholesterol levels were higher at the end of the trial, indicating improved lipid metabolism (Alvarado, Schoenlau 2016)
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